非天然的含疊氮基單糖的砌塊。疊氮化物部分可用于通過化學(xué)選擇性連接化學(xué)方法進(jìn)行修飾，包括 CuAAC、無銅點(diǎn)擊反應(yīng)或 Staudinger 連接。乙?；黾恿嗽谠S多溶劑中的溶解度，使這種試劑的處理更容易。Ac4ManNAz 是含疊氮基的代謝糖蛋白標(biāo)記試劑，能夠選擇性修飾蛋白質(zhì)，可用于細(xì)胞標(biāo)記、跟蹤和蛋白質(zhì)組學(xué)分析。Ac4ManNAz是一種含疊氮基的代謝糖蛋白標(biāo)記試劑，可以選擇性修飾蛋白質(zhì)。Ac4ManNAz 可用于細(xì)胞標(biāo)記、跟蹤和蛋白質(zhì)組學(xué)分析。Ac4ManNAz 含有 Azide 基團(tuán)，可以和含有 Alkyne 基團(tuán)的分子發(fā)生銅催化的疊氮-炔環(huán)加成反應(yīng)(CuAAc)。Ac4ManNAz 還可以和含有 DBCO 或 BCN 基團(tuán)的分子發(fā)生菌株促進(jìn)的炔-疊氮環(huán)加成反應(yīng) (SPAAC)。

靶點(diǎn)科技現(xiàn)貨N-azidoacetylmannosamine-tetraacylated (Ac4ManNAz) (CCT-1084)

精選參考文獻(xiàn)Selected References

1.Ranzinger, R., et al. (2020). Mass Spectrometric Method for the Unambiguous Profiling of Cellular Dynamic Glycosylation. ACS Chem. Biol., 15, 10, 2692-2701.

2.Loebel, C., et al. (2020). Metabolic Labeling to Probe the Spatiotemporal Accumulation of Matrix at the Chondrocyte–Hydrogel Interface. Adv. Funct. Mater.

3.Song, S., et al. (2020). In Situ One-Step Fluorescence Labeling Strategy of Exosomes via Bioorthogonal Click Chemistry for Real-Time Exosome Tracking In Vitro and In Vivo. Bioconjugate Chem., 31(5), 1562-74.

4.Kim, S. H., et al. (2014). Cell labeling and tracking method without distorted signals by phagocytosis of macrophages . Theranostics, 4 (4), 420-31.